Welcome to the HSP70 Sequence Database

Laurence A. Moran

The HSP70 multigene family is composed of genes related to the major heat shock protein of 70,000 daltons. The proteins encoded by these genes are usually abundant chaperones that are required for the proper folding and/or transport of proteins. They are present in all cells with the exception of a few species of archaebacteria.

This database is a collection of all known HSP70 sequences and structures. It includes distantly related members of the HSP70 Multigene Family and proposed family members that may or may not be homologous. The purpose of the database is to help sort out the confusing nomenclature and compensate for the lack of annotation in the sequence databases. The emphasis is on the evolution of HSP70 genes.

Like all biological databases, this is a work in progress. It will never be complete and will rarely include everything that has been published in the past few months. Nevertheless, I hope you find it useful. You can contact me at the email address listed at the bottom of this page. All comments are welcome, especially additions and corrections.